4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis

A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted (hetero)aromatic substituents were linked to N1 of the hydrazone in order t...

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Detalles Bibliográficos
Autores principales: Secci, Daniela, Carradori, Simone, Petzer, Anél, Guglielmi, Paolo, D’Ascenzio, Melissa, Chimenti, Paola, Bagetta, Donatella, Alcaro, Stefano, Zengin, Gokhan, Petzer, Jacobus P., Ortuso, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366404/
https://www.ncbi.nlm.nih.gov/pubmed/30727777
http://dx.doi.org/10.1080/14756366.2019.1571272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366404/
https://www.ncbi.nlm.nih.gov/pubmed/30727777
http://dx.doi.org/10.1080/14756366.2019.1571272

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