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Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure–activity relationship
α-Amylase has been considered an important therapeutic target for the management of type 2 diabetes mellitus (T2DM), decreasing postprandial hyperglycaemia (PPHG). In the present work, a panel of 40 structurally related flavonoids was tested, concerning their ability to inhibit α-amylase activity, u...
Autores principales: | Proença, Carina, Freitas, Marisa, Ribeiro, Daniela, Tomé, Sara M., Oliveira, Eduardo F. T., Viegas, Matilde F., Araújo, Alberto N., Ramos, Maria J., Silva, Artur M. S., Fernandes, Pedro A., Fernandes, Eduarda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366418/ https://www.ncbi.nlm.nih.gov/pubmed/30724629 http://dx.doi.org/10.1080/14756366.2018.1558221 |
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