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Endocardial Notch Signaling Promotes Cardiomyocyte Proliferation in the Regenerating Zebrafish Heart through Wnt Pathway Antagonism

Previous studies demonstrate that the regenerative zebrafish heart responds to injury by upregulating Notch receptors in the endocardium and epicardium. Moreover, global suppression of Notch activity following injury impairs cardiomyocyte proliferation and induces scarring. However, the lineage-spec...

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Detalles Bibliográficos
Autores principales:	Zhao, Long, Ben-Yair, Raz, Burns, Caroline E., Burns, C. Geoffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366857/ https://www.ncbi.nlm.nih.gov/pubmed/30650349 http://dx.doi.org/10.1016/j.celrep.2018.12.048

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