DNA methylation GrimAge strongly predicts lifespan and healthspan

It was unknown whether plasma protein levels can be estimated based on DNA methylation (DNAm) levels, and if so, how the resulting surrogates can be consolidated into a powerful predictor of lifespan. We present here, seven DNAm-based estimators of plasma proteins including those of plasminogen acti...

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Detalles Bibliográficos
Autores principales: Lu, Ake T., Quach, Austin, Wilson, James G., Reiner, Alex P., Aviv, Abraham, Raj, Kenneth, Hou, Lifang, Baccarelli, Andrea A., Li, Yun, Stewart, James D., Whitsel, Eric A., Assimes, Themistocles L., Ferrucci, Luigi, Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366976/
https://www.ncbi.nlm.nih.gov/pubmed/30669119
http://dx.doi.org/10.18632/aging.101684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366976/
https://www.ncbi.nlm.nih.gov/pubmed/30669119
http://dx.doi.org/10.18632/aging.101684

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