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DNA methylation GrimAge strongly predicts lifespan and healthspan
It was unknown whether plasma protein levels can be estimated based on DNA methylation (DNAm) levels, and if so, how the resulting surrogates can be consolidated into a powerful predictor of lifespan. We present here, seven DNAm-based estimators of plasma proteins including those of plasminogen acti...
Autores principales: | Lu, Ake T., Quach, Austin, Wilson, James G., Reiner, Alex P., Aviv, Abraham, Raj, Kenneth, Hou, Lifang, Baccarelli, Andrea A., Li, Yun, Stewart, James D., Whitsel, Eric A., Assimes, Themistocles L., Ferrucci, Luigi, Horvath, Steve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366976/ https://www.ncbi.nlm.nih.gov/pubmed/30669119 http://dx.doi.org/10.18632/aging.101684 |
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