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Structure of the post-translational protein translocation machinery of the ER membrane

Many proteins must translocate through the protein-conducting Sec61 channel in the eukaryotic endoplasmic reticulum membrane or the SecY channel in the prokaryotic plasma membrane(1,2). Proteins with hydrophobic signal sequences are first recognized by the signal recognition particle (SRP)(3,4) and...

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Detalles Bibliográficos
Autores principales:	Wu, Xudong, Cabanos, Cerrone, Rapoport, Tom A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367035/ https://www.ncbi.nlm.nih.gov/pubmed/30644436 http://dx.doi.org/10.1038/s41586-018-0856-x

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