Cargando…

Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report

INTRODUCTION: Antiretroviral drugs are known to cause osteoporosis making the bones susceptible to fracture. Osteoporotic fractures are majorly seen in the vertebral bodies. Pathological fractures need to be fixed without much delay to start mobilization of the patients. CASE REPORT: The present cas...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramanath, Sharath Kittanakere, Shah, Rahul Hemant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Orthopaedic Research Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367293/
https://www.ncbi.nlm.nih.gov/pubmed/30740382
http://dx.doi.org/10.13107/jocr.2250-0685.1220
_version_ 1783393756608724992
author Ramanath, Sharath Kittanakere
Shah, Rahul Hemant
author_facet Ramanath, Sharath Kittanakere
Shah, Rahul Hemant
author_sort Ramanath, Sharath Kittanakere
collection PubMed
description INTRODUCTION: Antiretroviral drugs are known to cause osteoporosis making the bones susceptible to fracture. Osteoporotic fractures are majorly seen in the vertebral bodies. Pathological fractures need to be fixed without much delay to start mobilization of the patients. CASE REPORT: The present case describes a 72-year-old male who was diagnosed to be human immunodeficiency virus-positive 11 months back for which the patient was on a combination of antiretroviral therapy for 11 months. The patient was a farmer by occupation. The patient presented to us with left sided hip pain for1 week with no history of trauma or fall. The patient was able to walk approximately 100m with the help of a height adjustable walker. However, activities such as squatting and sitting cross-legged were restricted for1 week. Radiographic examination revealed a fracture of the left neck of the femur. The patient was evaluated for metastasis the investigations for which were negative. Bipolar hemiarthroplasty of the hip was done since radiographically and intraoperatively no changes were noted in the acetabulum which would have changed the plan to total hip replacement. Following the surgery, patient started walking full-weight bearing from the very next day after surgery. CONCLUSION: This case concludes the potential of antiretroviral drugs such as abacavir, lamivudine and efavirenz to cause pathological fractures which has never been described in literature before.
format Online
Article
Text
id pubmed-6367293
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Indian Orthopaedic Research Group
record_format MEDLINE/PubMed
spelling pubmed-63672932019-02-08 Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report Ramanath, Sharath Kittanakere Shah, Rahul Hemant J Orthop Case Rep Case Report INTRODUCTION: Antiretroviral drugs are known to cause osteoporosis making the bones susceptible to fracture. Osteoporotic fractures are majorly seen in the vertebral bodies. Pathological fractures need to be fixed without much delay to start mobilization of the patients. CASE REPORT: The present case describes a 72-year-old male who was diagnosed to be human immunodeficiency virus-positive 11 months back for which the patient was on a combination of antiretroviral therapy for 11 months. The patient was a farmer by occupation. The patient presented to us with left sided hip pain for1 week with no history of trauma or fall. The patient was able to walk approximately 100m with the help of a height adjustable walker. However, activities such as squatting and sitting cross-legged were restricted for1 week. Radiographic examination revealed a fracture of the left neck of the femur. The patient was evaluated for metastasis the investigations for which were negative. Bipolar hemiarthroplasty of the hip was done since radiographically and intraoperatively no changes were noted in the acetabulum which would have changed the plan to total hip replacement. Following the surgery, patient started walking full-weight bearing from the very next day after surgery. CONCLUSION: This case concludes the potential of antiretroviral drugs such as abacavir, lamivudine and efavirenz to cause pathological fractures which has never been described in literature before. Indian Orthopaedic Research Group 2018 /pmc/articles/PMC6367293/ /pubmed/30740382 http://dx.doi.org/10.13107/jocr.2250-0685.1220 Text en Copyright: © Indian Orthopaedic Research Group http://creativecommons.org/licenses/by-nc/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ramanath, Sharath Kittanakere
Shah, Rahul Hemant
Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report
title Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report
title_full Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report
title_fullStr Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report
title_full_unstemmed Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report
title_short Non-traumatic Unilateral Femur Neck Fracture in a Human Immunodeficiency Virus-Positive Septuagenarian Indian Male: A Unique Case Report
title_sort non-traumatic unilateral femur neck fracture in a human immunodeficiency virus-positive septuagenarian indian male: a unique case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367293/
https://www.ncbi.nlm.nih.gov/pubmed/30740382
http://dx.doi.org/10.13107/jocr.2250-0685.1220
work_keys_str_mv AT ramanathsharathkittanakere nontraumaticunilateralfemurneckfractureinahumanimmunodeficiencyviruspositiveseptuagenarianindianmaleauniquecasereport
AT shahrahulhemant nontraumaticunilateralfemurneckfractureinahumanimmunodeficiencyviruspositiveseptuagenarianindianmaleauniquecasereport