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The orbitofrontal cortex modulates parenting stress in the maternal brain

Many mothers are adaptive, deploying successful coping strategies that mitigate the deleterious effects of parenting stress on caregiving, nevertheless, the neural mechanisms underlying these adaptive responses remain unclear. We utilized functional magnetic resonance imaging to investigate brain ac...

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Autores principales: Noriuchi, Madoka, Kikuchi, Yoshiaki, Mori, Kumiko, Kamio, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367346/
https://www.ncbi.nlm.nih.gov/pubmed/30733605
http://dx.doi.org/10.1038/s41598-018-38402-9
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author Noriuchi, Madoka
Kikuchi, Yoshiaki
Mori, Kumiko
Kamio, Yoko
author_facet Noriuchi, Madoka
Kikuchi, Yoshiaki
Mori, Kumiko
Kamio, Yoko
author_sort Noriuchi, Madoka
collection PubMed
description Many mothers are adaptive, deploying successful coping strategies that mitigate the deleterious effects of parenting stress on caregiving, nevertheless, the neural mechanisms underlying these adaptive responses remain unclear. We utilized functional magnetic resonance imaging to investigate brain activity in 28 healthy mothers of typically developing, 2-to-3-year-old children in response to the feeding behavior of their own children versus that of other children. We then examined the correlation between maternal brain activation and subjective feelings of parenting stress. Brain regions associated with maternal motivation including the orbitofrontal cortex (OFC), ventral pallidum, periaqueductal gray (PAG), dorsal raphe nucleus (DRN), and anterior insular cortex (AIC)—as well as those associated with the recognition of one’s own child’s state (e.g., cerebellum)—exhibited significant activation in response to their own children. While mothers with higher activation in the OFC showed less parenting stress related to one’s sense of competence in the parental role, mothers with higher co-activation of the OFC with both of the AIC and PAG/DRN, and with the cerebellum showed less parenting stress caused by child characteristics. Our findings suggest that well-balanced maternal brain mechanisms integrated by the OFC may provide effective adaptive responses in daily parenting scenarios.
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spelling pubmed-63673462019-02-11 The orbitofrontal cortex modulates parenting stress in the maternal brain Noriuchi, Madoka Kikuchi, Yoshiaki Mori, Kumiko Kamio, Yoko Sci Rep Article Many mothers are adaptive, deploying successful coping strategies that mitigate the deleterious effects of parenting stress on caregiving, nevertheless, the neural mechanisms underlying these adaptive responses remain unclear. We utilized functional magnetic resonance imaging to investigate brain activity in 28 healthy mothers of typically developing, 2-to-3-year-old children in response to the feeding behavior of their own children versus that of other children. We then examined the correlation between maternal brain activation and subjective feelings of parenting stress. Brain regions associated with maternal motivation including the orbitofrontal cortex (OFC), ventral pallidum, periaqueductal gray (PAG), dorsal raphe nucleus (DRN), and anterior insular cortex (AIC)—as well as those associated with the recognition of one’s own child’s state (e.g., cerebellum)—exhibited significant activation in response to their own children. While mothers with higher activation in the OFC showed less parenting stress related to one’s sense of competence in the parental role, mothers with higher co-activation of the OFC with both of the AIC and PAG/DRN, and with the cerebellum showed less parenting stress caused by child characteristics. Our findings suggest that well-balanced maternal brain mechanisms integrated by the OFC may provide effective adaptive responses in daily parenting scenarios. Nature Publishing Group UK 2019-02-07 /pmc/articles/PMC6367346/ /pubmed/30733605 http://dx.doi.org/10.1038/s41598-018-38402-9 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Noriuchi, Madoka
Kikuchi, Yoshiaki
Mori, Kumiko
Kamio, Yoko
The orbitofrontal cortex modulates parenting stress in the maternal brain
title The orbitofrontal cortex modulates parenting stress in the maternal brain
title_full The orbitofrontal cortex modulates parenting stress in the maternal brain
title_fullStr The orbitofrontal cortex modulates parenting stress in the maternal brain
title_full_unstemmed The orbitofrontal cortex modulates parenting stress in the maternal brain
title_short The orbitofrontal cortex modulates parenting stress in the maternal brain
title_sort orbitofrontal cortex modulates parenting stress in the maternal brain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367346/
https://www.ncbi.nlm.nih.gov/pubmed/30733605
http://dx.doi.org/10.1038/s41598-018-38402-9
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