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Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis

During embryogenesis, exocrine and endocrine pancreatic tissues are formed in distinct regions within the branched ductal structure in mice. We previously reported that exocrine-specific inactivation of Pdx1 by Elastase-Cre caused not only hypoplastic exocrine formation but also substantial endocrin...

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Detalles Bibliográficos
Autores principales:	Hirata, Koji, Kodama, Sota, Nakano, Yasuhiro, Minaki-Nakagawa, Yasuko, Aoyama, Yoshiki, Sakikubo, Morito, Goto, Toshihiko, Yoshida, Masahiro, Masui, Toshihiko, Yamamoto, Takuya, Uemoto, Shinji, Kawaguchi, Yoshiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367380/ https://www.ncbi.nlm.nih.gov/pubmed/30733468 http://dx.doi.org/10.1038/s41598-018-38062-9

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