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Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors

Phosphatidylserine externalization is an early molecular signature for apoptosis. In many retinal degenerative diseases, photoreceptor neurons die by apoptosis. Here, we report utility of the phosphatidylserine-binding conjugate of Bis(zinc(II)-dipicolylamine (Zn-DPA) with Texas-red (PSVue-550) in t...

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Detalles Bibliográficos
Autores principales: Mazzoni, Francesca, Müller, Claudia, DeAssis, Jonathan, Lew, Deborah, Leevy, W. Matthew, Finnemann, Silvia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367443/
https://www.ncbi.nlm.nih.gov/pubmed/30733587
http://dx.doi.org/10.1038/s41598-018-38363-z

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