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Nanoparticle enhanced MRI can monitor macrophage response to CD47 mAb immunotherapy in osteosarcoma

CD47 monoclonal antibodies (mAbs) activate tumor-associated macrophages (TAMs) in sarcomas to phagocytose and eliminate cancer cells. Though CD47 mAbs have entered clinical trials, diagnostic tests for monitoring therapy response in vivo are currently lacking. Ferumoxytol is an FDA-approved iron sup...

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Detalles Bibliográficos
Autores principales:	Mohanty, Suchismita, Yerneni, Ketan, Theruvath, Johanna Lena, Graef, Claus Moritz, Nejadnik, Hossein, Lenkov, Olga, Pisani, Laura, Rosenberg, Jarrett, Mitra, Siddhartha, Cordero, Alejandro Sweet, Cheshier, Samuel, Daldrup-Link, Heike E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367456/ https://www.ncbi.nlm.nih.gov/pubmed/30674867 http://dx.doi.org/10.1038/s41419-018-1285-3

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