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Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping

Analysis of antibody repertoires by high-throughput sequencing is of major importance in understanding adaptive immune responses. Our knowledge of variations in the genomic loci encoding immunoglobulin genes is incomplete, resulting in conflicting VDJ gene assignments and biased genotype and haploty...

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Detalles Bibliográficos
Autores principales:	Gidoni, Moriah, Snir, Omri, Peres, Ayelet, Polak, Pazit, Lindeman, Ida, Mikocziova, Ivana, Sarna, Vikas Kumar, Lundin, Knut E. A., Clouser, Christopher, Vigneault, Francois, Collins, Andrew M., Sollid, Ludvig M., Yaari, Gur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367474/ https://www.ncbi.nlm.nih.gov/pubmed/30733445 http://dx.doi.org/10.1038/s41467-019-08489-3

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