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Pseudotyping retrovirus like particles vaccine candidates with Hepatitis C virus envelope protein E2 requires the cellular expression of CD81

Hepatitis C virus (HCV) infects 3% of world population being responsible for nearly half a million deaths annually urging the need for a prophylactic vaccine. Retrovirus like particles are commonly used scaffolds for antigens presentation being the core of diverse vaccine candidates. The immunogenic...

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Detalles Bibliográficos
Autores principales: Soares, Hugo R., Castro, Rute, Tomás, Hélio A., Carrondo, Manuel J. T., Alves, Paula M., Coroadinha, Ana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367494/
https://www.ncbi.nlm.nih.gov/pubmed/30729353
http://dx.doi.org/10.1186/s13568-019-0741-5