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IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways
Ifosfamide and other oxazaphosphorines can result in hemorrhagic cystitis, a constellation of complications caused by acrolein metabolites. We previously showed that a single dose of IPSE (Interleukin-4-inducing principle from Schistosoma eggs), a schistosome-derived host modulatory protein, can ame...
Autores principales: | Mbanefo, Evaristus C., Le, Loc, Zee, Rebecca, Banskota, Nirad, Ishida, Kenji, Pennington, Luke F., Odegaard, Justin I., Jardetzky, Theodore S., Alouffi, Abdulaziz, Falcone, Franco H., Hsieh, Michael H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367514/ https://www.ncbi.nlm.nih.gov/pubmed/30733505 http://dx.doi.org/10.1038/s41598-018-38274-z |
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