Cargando…

RRM2 is a potential prognostic biomarker with functional significance in glioma

Glioma is one of the most common brain tumors, suggesting the importance of investigating the molecular mechanism of gliomas. We studied the roles of Ribonucleotide Reductase Regulatory Subunit M2 (RRM2) in glioma. Expressions of RRM2 are higher in glioma tissues evidenced by TCGA data, western blot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Hongzhi, Yang, Bingya, Zhang, Hao, Song, Jingwei, Zhang, Yenan, Xing, Jicheng, Yang, Zhihui, Wei, Changyong, Xu, Tuoye, Yu, Zhennan, Xu, Zhipeng, Hou, Min, Ji, Minjun, Zhang, Yansong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367584/ https://www.ncbi.nlm.nih.gov/pubmed/30745840 http://dx.doi.org/10.7150/ijbs.30114

Ejemplares similares

PPAR-γ Agonist Alleviates Liver and Spleen Pathology via Inducing Treg Cells during Schistosoma japonicum Infection
por: Zhu, Yuxiao, et al.
Publicado: (2018)

Bioinformatics analysis revealing prognostic significance of RRM2 gene in breast cancer
por: Chen, Wei-xian, et al.
Publicado: (2019)

HELLPAR/RRM2 axis related to HMMR as novel prognostic biomarker in gliomas
por: Zhu, Huaxin, et al.
Publicado: (2023)

Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice
por: Luo, Xiaofeng, et al.
Publicado: (2017)

The Clinical and Prognostic Significance of Ribonucleotide Reductase Subunits RRM1 and RRM2 mRNA Levels in Patients with Chronic Lymphocytic Leukemia
por: Chatzidavid, Sevastianos, et al.
Publicado: (2023)

RRM2 expression in different molecular subtypes of breast cancer and its prognostic significance
por: Abdel-Rahman, Manar Ahmed, et al.
Publicado: (2022)

Absence of Batf3 results in reduced liver pathology in mice infected with Schistosoma japonicum
por: Chen, Lin, et al.
Publicado: (2017)

ASF1B promotes cervical cancer progression through stabilization of CDK9
por: Liu, Xinjian, et al.
Publicado: (2020)

Identification of CDKL3 as a critical regulator in development of glioma through regulating RRM2 and the JNK signaling pathway
por: Cui, Yong, et al.
Publicado: (2021)

RRM1 *151A>T, RRM1 ‐756T>C, and RRM1 ‐585T>Gis associated with increased susceptibility of lung cancer in Chinese patients
por: Xu, Xiao‐Ling, et al.
Publicado: (2016)

Independent prognostic implications of RRM2 in lung adenocarcinoma
por: Ma, Chao, et al.
Publicado: (2020)

SjTat-TPI facilitates adaptive T-cell responses and reduces hepatic pathology during Schistosoma japonicum infection in BALB/c mice
por: Zhang, Wenyue, et al.
Publicado: (2015)

Evaluation of factors influencing the guide to read biomedical English literature course for Chinese new medical postgraduates—a multiple regression analysis
por: Xu, Zhipeng, et al.
Publicado: (2019)

Expression of Genomic Instability-Related Molecules: Cyclin F, RRM2 and SPDL1 and Their Prognostic Significance in Pancreatic Adenocarcinoma
por: Klimaszewska-Wiśniewska, Anna, et al.
Publicado: (2021)

Prognostic significance of age related genes in patients with lower grade glioma
por: Wang, Haiwei, et al.
Publicado: (2020)

Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas
por: Wu, Xing, et al.
Publicado: (2016)

Prognostic Significance of MicroRNAs in Glioma: A Systematic Review and Meta-Analysis
por: Zhang, Yanming, et al.
Publicado: (2019)

Erratum to: Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas
por: Wu, Xing, et al.
Publicado: (2016)

Differential and Prognostic Significance of HOXB7 in Gliomas
por: Zhou, Xingang, et al.
Publicado: (2021)

Expression and prognostic significance of CTBP2 in human gliomas
por: Wang, Yong, et al.
Publicado: (2016)

Clinicopathological and Prognostic Significance of ABCC3 in Human Glioma
por: Fang, Dan-Dong, et al.
Publicado: (2021)

Overexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesis
por: Zhang, Keqiang, et al.
Publicado: (2009)

Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
por: Ohmura, Shunya, et al.
Publicado: (2021)

Clinical and prognostic significance of high-mobility group box-1 in human gliomas
por: WANG, XIN-JUN, et al.
Publicado: (2015)

Aberrant expression of long non-coding RNAs (lncRNAs) is involved in brain glioma development
por: Ding, Yi, et al.
Publicado: (2019)

RRM2‑mediated Wnt/β‑catenin signaling pathway activation in lung adenocarcinoma: A potential prognostic biomarker
por: Jiang, Yongjie, et al.
Publicado: (2023)

Comprehensive Landscape of RRM2 with Immune Infiltration in Pan-Cancer
por: Zhou, Zijian, et al.
Publicado: (2022)

A missense mutation in RRM1 contributes to animal tameness
por: Dou, Mingle, et al.
Publicado: (2023)

Prognostic significance of TMEM131L in glioma and establishment of oxidative stress prognostic model
por: Shan, Li, et al.
Publicado: (2023)

RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer
por: Yang, Yueyue, et al.
Publicado: (2020)

Expression profiles and prognostic significance of WNT family members in glioma via bioinformatic analysis
por: Xu, Anqi, et al.
Publicado: (2020)

Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine
por: Jørgensen, Charlotte LT, et al.
Publicado: (2013)

Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition
por: Krepl, Miroslav, et al.
Publicado: (2017)

Prognostic role of survivin in patients with glioma
por: Zhang, Sunfu, et al.
Publicado: (2018)

Comprehensive Analysis of PD-1 Gene Expression, Immune Characteristics and Prognostic Significance in 1396 Glioma Patients
por: Liu, Chaojun, et al.
Publicado: (2020)

Identification of EMT-Related Genes and Prognostic Signature With Significant Implications on Biological Properties and Oncology Treatment of Lower Grade Gliomas
por: Wu, Jiasheng, et al.
Publicado: (2022)

Prognostic significance of ARL9 and its methylation in low-grade glioma
por: Tan, Yutang, et al.
Publicado: (2020)

Zinc Binds to RRM2 Peptide of TDP-43
por: Golovin, Andrey V., et al.
Publicado: (2020)

Interleukin-33 in human gliomas: Expression and prognostic significance
por: GRAMATZKI, DOROTHEE, et al.
Publicado: (2016)

Characterization and prognostic significance of alternative splicing events in lower‐grade diffuse gliomas
por: Zhao, Zheng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7sduvrhbso386fkqa87m43igb8