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TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis
BACKGROUND: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has previously been demonstrated to play a pro-inflammatory role in allergic airways disease and COPD through the upregulation of the E3 ubiquitin ligase MID1 and the subsequent deactivation of protein phosphatase 2A (PP2A)...
Autores principales: | Collison, Adam M., Li, Junyao, de Siqueira, Ana Pereira, Lv, Xuejiao, Toop, Hamish D., Morris, Jonathan C., Starkey, Malcolm R., Hansbro, Philip M., Zhang, Jie, Mattes, Joerg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367767/ https://www.ncbi.nlm.nih.gov/pubmed/30732588 http://dx.doi.org/10.1186/s12890-019-0786-x |
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