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Chromosome rearrangements shape the diversification of secondary metabolism in the cyclosporin producing fungus Tolypocladium inflatum
BACKGROUND: Genes involved in production of secondary metabolites (SMs) in fungi are exceptionally diverse. Even strains of the same species may exhibit differences in metabolite production, a finding that has important implications for drug discovery. Unlike in other eukaryotes, genes producing SMs...
Autores principales: | Olarte, Rodrigo A., Menke, Jon, Zhang, Ying, Sullivan, Shawn, Slot, Jason C., Huang, Yinyin, Badalamenti, Jonathan P., Quandt, Alisha C., Spatafora, Joseph W., Bushley, Kathryn E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367777/ https://www.ncbi.nlm.nih.gov/pubmed/30732559 http://dx.doi.org/10.1186/s12864-018-5399-x |
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