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Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta

BACKGROUND: It is well established that obesity is associated with dysregulation of the ratio between the two major adipokines leptin and adiponectin. Furthermore, it was recently reported that maternal obesity has a significant impact on placental development. Leptin and adiponectin are present at...

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Detalles Bibliográficos
Autores principales: Nogues, Perrine, Dos Santos, Esther, Jammes, Hélène, Berveiller, Paul, Arnould, Lucie, Vialard, François, Dieudonné, Marie-Noëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367801/
https://www.ncbi.nlm.nih.gov/pubmed/30732639
http://dx.doi.org/10.1186/s13148-019-0612-6