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SPAG5 upregulation contributes to enhanced c-MYC transcriptional activity via interaction with c-MYC binding protein in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype that lacks effective therapeutic targets. Sperm-associated antigen 5 (SPAG5) is a mitotic spindle-associated protein that is involved in various biological processes in cervical cancer and bladder urothelial carc...

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Detalles Bibliográficos
Autores principales:	Li, Ming, Li, Anqi, Zhou, Shuling, Lv, Hong, Yang, Wentao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367803/ https://www.ncbi.nlm.nih.gov/pubmed/30736840 http://dx.doi.org/10.1186/s13045-019-0700-2

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