Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms

Multiple sclerosis (MS) is a chronic immune-mediated disease of the spinal cord and brain. Many studies have shown that smoking and passive smoking are key environmental risk factors for MS. Here, we provide an overview of the human leukocyte antigen (HLA) gene studies on smoking and MS risk, and we...

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Autores principales: Wang, Zhaowei, Xie, Jianpin, Wu, Chenglong, Xiao, Guirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367889/
https://www.ncbi.nlm.nih.gov/pubmed/30703074
http://dx.doi.org/10.12659/MSM.912863
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author Wang, Zhaowei
Xie, Jianpin
Wu, Chenglong
Xiao, Guirong
author_facet Wang, Zhaowei
Xie, Jianpin
Wu, Chenglong
Xiao, Guirong
author_sort Wang, Zhaowei
collection PubMed
description Multiple sclerosis (MS) is a chronic immune-mediated disease of the spinal cord and brain. Many studies have shown that smoking and passive smoking are key environmental risk factors for MS. Here, we provide an overview of the human leukocyte antigen (HLA) gene studies on smoking and MS risk, and we discuss recent studies on between epigenetics and smoking-induced MS. In addition, in this review we also summarize current research advances in biological pathways and smoking-induced MS. This review provides an overview of studies on the association between smoking, passive smoking, and MS susceptibility, and the underlying molecular mechanism.
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spelling pubmed-63678892019-02-15 Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms Wang, Zhaowei Xie, Jianpin Wu, Chenglong Xiao, Guirong Med Sci Monit Review Articles Multiple sclerosis (MS) is a chronic immune-mediated disease of the spinal cord and brain. Many studies have shown that smoking and passive smoking are key environmental risk factors for MS. Here, we provide an overview of the human leukocyte antigen (HLA) gene studies on smoking and MS risk, and we discuss recent studies on between epigenetics and smoking-induced MS. In addition, in this review we also summarize current research advances in biological pathways and smoking-induced MS. This review provides an overview of studies on the association between smoking, passive smoking, and MS susceptibility, and the underlying molecular mechanism. International Scientific Literature, Inc. 2019-01-31 /pmc/articles/PMC6367889/ /pubmed/30703074 http://dx.doi.org/10.12659/MSM.912863 Text en © Med Sci Monit, 2019 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Review Articles
Wang, Zhaowei
Xie, Jianpin
Wu, Chenglong
Xiao, Guirong
Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms
title Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms
title_full Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms
title_fullStr Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms
title_full_unstemmed Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms
title_short Correlation Between Smoking and Passive Smoking with Multiple Sclerosis and the Underlying Molecular Mechanisms
title_sort correlation between smoking and passive smoking with multiple sclerosis and the underlying molecular mechanisms
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367889/
https://www.ncbi.nlm.nih.gov/pubmed/30703074
http://dx.doi.org/10.12659/MSM.912863
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