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Expedited isolation of natural product peptidyl-tRNA hydrolase inhibitors from a Pth1 affinity column

New antibiotics and new antibiotic targets are needed to counter the development of bacterial drug resistance that threatens to return the human population to the pre-antibiotic era. Bacterial peptidyl-tRNA hydrolase (Pth1) is a promising new antibiotic target in the early stages of development. Whi...

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Detalles Bibliográficos
Autores principales: Sethi, Harkirat S., Osier, Jessica L., Burks, Geordan L., Lamar, Jennifer F., McFeeters, Hana, McFeeters, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368095/
https://www.ncbi.nlm.nih.gov/pubmed/30740515
http://dx.doi.org/10.3934/molsci.2017.2.175