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Oxygen in the tumor microenvironment: effects on dendritic cell function

Solid tumors grow at a high speed leading to insufficient blood supply to tumor cells. This makes the tumor hypoxic, resulting in the Warburg effect and an increased generation of reactive oxygen species (ROS). Hypoxia and ROS affect immune cells in the tumor micro-environment, thereby affecting the...

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Detalles Bibliográficos
Autores principales: Paardekooper, Laurent M., Vos, Willemijn, van den Bogaart, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368231/
https://www.ncbi.nlm.nih.gov/pubmed/30783517
http://dx.doi.org/10.18632/oncotarget.26608