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Oxygen in the tumor microenvironment: effects on dendritic cell function
Solid tumors grow at a high speed leading to insufficient blood supply to tumor cells. This makes the tumor hypoxic, resulting in the Warburg effect and an increased generation of reactive oxygen species (ROS). Hypoxia and ROS affect immune cells in the tumor micro-environment, thereby affecting the...
Autores principales: | Paardekooper, Laurent M., Vos, Willemijn, van den Bogaart, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368231/ https://www.ncbi.nlm.nih.gov/pubmed/30783517 http://dx.doi.org/10.18632/oncotarget.26608 |
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