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Comparison of systemic and mucosal immunization with replicating Single cycle Adenoviruses

HIV-1 infections occur during sexual contact at mucosal surfaces. Vaccines need to provide mucosal barrier protection and stimulate systemic immune responses to control HIV spread. Most vaccines are delivered by systemic immunization via intramuscular (IM) injection route. While this can drive syste...

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Detalles Bibliográficos
Autores principales: Matchett, William E, Anguiano-Zarate, Stephanie S, Barry, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368267/
https://www.ncbi.nlm.nih.gov/pubmed/30740532
http://dx.doi.org/10.15761/GVI.1000128