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Anti-CD8 monoclonal antibody-mediated depletion alters the phenotype and behavior of surviving CD8+ T cells
It is common practice for researchers to use antibodies to remove a specific cell type to infer its function. However, it is difficult to completely eliminate a cell type and there is often limited or no information as to how the cells which survive depletion are affected. This is particularly impor...
Autores principales: | Cross, Eric W., Blain, Trevor J., Mathew, Divij, Kedl, Ross M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368275/ https://www.ncbi.nlm.nih.gov/pubmed/30735510 http://dx.doi.org/10.1371/journal.pone.0211446 |
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