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Insulin resistance disrupts epithelial repair and niche-progenitor Fgf signaling during chronic liver injury
Insulin provides important information to tissues about feeding behavior and energy status. Defective insulin signaling is associated with ageing, tissue dysfunction, and impaired wound healing. In the liver, insulin resistance leads to chronic damage and fibrosis, but it is unclear how tissue-repai...
Autores principales: | Manzano-Núñez, Fátima, Arámbul-Anthony, María José, Galán Albiñana, Amparo, Leal Tassias, Aranzazu, Acosta Umanzor, Carlos, Borreda Gascó, Irene, Herrera, Antonio, Forteza Vila, Jerónimo, Burks, Deborah J., Noon, Luke A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368328/ https://www.ncbi.nlm.nih.gov/pubmed/30695023 http://dx.doi.org/10.1371/journal.pbio.2006972 |
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