The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses

The initial steps in the synthesis of leukotrienes are the translocation of 5-lipoxygenase (5-LO) to the nuclear envelope and its subsequent association with its scaffold protein 5-lipoxygenase-activating protein (FLAP). A major gap in our understanding of this process is the knowledge of how the or...

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Detalles Bibliográficos
Autores principales: Schmider, Angela B., Vaught, Melissa, Bauer, Nicholas C., Elliott, Hunter L., Godin, Matthew D., Ellis, Giorgianna E., Nigrovic, Peter A., Soberman, Roy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368329/
https://www.ncbi.nlm.nih.gov/pubmed/30735559
http://dx.doi.org/10.1371/journal.pone.0211943

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