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Development of novel lipidic particles for siRNA delivery that are highly effective after 12 months storage
Liposomes are versatile and well-proven as a means to deliver nucleic acids into cells. Most of the formulation procedures used are labour intensive and result in unstable end products. We have previously reported on the development of a simple, yet efficient, hydration-of-freeze-dried-matrix (HFDM)...
Autores principales: | Clarke, Daniel, Idris, Adi, McMillan, Nigel A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368384/ https://www.ncbi.nlm.nih.gov/pubmed/30735545 http://dx.doi.org/10.1371/journal.pone.0211954 |
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