Dynamics and Selective Remodeling of the DNA Binding Domains of RPA

Replication protein A (RPA) coordinates important DNA metabolic events by stabilizing single-strand DNA (ssDNA) intermediates, activating the DNA damage response and handing off ssDNA to appropriate downstream players. Six DNA binding domains (DBDs) in RPA promote high affinity binding to ssDNA yet...

Descripción completa

Detalles Bibliográficos
Autores principales: Pokhrel, Nilisha, Caldwell, Colleen C., Corless, Elliot I., Tillison, Emma A., Tibbs, Joseph, Jocic, Nina, Tabei, S. M. Ali, Wold, Marc S., Spies, Maria, Antony, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368398/
https://www.ncbi.nlm.nih.gov/pubmed/30723327
http://dx.doi.org/10.1038/s41594-018-0181-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368398/
https://www.ncbi.nlm.nih.gov/pubmed/30723327
http://dx.doi.org/10.1038/s41594-018-0181-y

Ejemplares similares