The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer

The biological role of miR-500a-5p has not yet been reported in the context of colorectal cancer (CRC). Here, we show that miR-500a-5p expression is decreased in CRC tissues compared with adjacent normal tissues. Low miR-500a-5p expression is associated with malignant progression. Moreover, transfec...

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Detalles Bibliográficos
Autores principales: Tang, Weimei, Zhou, Weijie, Xiang, Li, Wu, Xiaosheng, Zhang, Pei, Wang, Jing, Liu, Guangnan, Zhang, Wenjing, Peng, Ying, Huang, Xiaoting, Cai, Jianqun, Bai, Yang, Bai, Lan, Zhu, Wei, Gu, Hongxiang, Xiong, Jing, Ye, Chen, Li, Aimin, Liu, Side, Wang, Jide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368584/
https://www.ncbi.nlm.nih.gov/pubmed/30737378
http://dx.doi.org/10.1038/s41467-018-08225-3

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