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A network biology approach to unraveling inherited axonopathies

Inherited axonopathies represent a spectrum of disorders unified by the common pathological mechanism of length-dependent axonal degeneration. Progressive axonal degeneration can lead to both Charcot-Marie-Tooth type 2 (CMT2) and Hereditary Spastic Paraplegia (HSP) depending on the affected neurons:...

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Detalles Bibliográficos
Autores principales: Bis-Brewer, Dana M., Danzi, Matt C., Wuchty, Stefan, Züchner, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368620/
https://www.ncbi.nlm.nih.gov/pubmed/30737464
http://dx.doi.org/10.1038/s41598-018-37119-z

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