The in vivo specificity of synaptic Gβ and Gγ subunits to the α(2a) adrenergic receptor at CNS synapses

G proteins are major transducers of signals from G-protein coupled receptors (GPCRs). They are made up of α, β, and γ subunits, with 16 Gα, 5 Gβ and 12 Gγ subunits. Though much is known about the specificity of Gα subunits, the specificity of Gβγs activated by a given GPCR and that activate each eff...

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Detalles Bibliográficos
Autores principales: Yim, Yun Young, Betke, Katherine M., McDonald, W. Hayes, Gilsbach, Ralf, Chen, Yunjia, Hyde, Karren, Wang, Qin, Hein, Lutz, Hamm, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368627/
https://www.ncbi.nlm.nih.gov/pubmed/30737458
http://dx.doi.org/10.1038/s41598-018-37222-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368627/
https://www.ncbi.nlm.nih.gov/pubmed/30737458
http://dx.doi.org/10.1038/s41598-018-37222-1

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