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Combining I148M and E167K variants to improve risk prediction for nonalcoholic fatty liver disease in Qingdao Han population, China
BACKGROUND: PNPLA3 I148M variant and TM6SF2 E167K variant are recognized as the major genetic modifiers of nonalcoholic fatty liver disease (NAFLD). The present study sought to evaluate the potential additive effect of the two variants on the risk of NAFLD in Qingdao Han Population, China. METHODS:...
Autores principales: | Chen, Li-Zhen, Ding, Hong-Yun, Liu, Shou-Sheng, Liu, Qun, Jiang, Xiang-Jun, Xin, Yong-Ning, Xuan, Shi-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368685/ https://www.ncbi.nlm.nih.gov/pubmed/30738435 http://dx.doi.org/10.1186/s12944-019-0992-9 |
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