Widely metastatic IDH1-mutant glioblastoma with oligodendroglial features and atypical molecular findings: a case report and review of current challenges in molecular diagnostics

BACKGROUND: Gliomas with 1p/19q-codeletion as well as mutation of isocitrate dehydrogenase (IDH) 1 are typically characterized as oligodendrogliomas with comparatively good response to treatment with radiation and chemotherapy. CASE PRESENTATION: We present the case of a 28-year-old man with an IDH1...

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Detalles Bibliográficos
Autores principales: Romo, Carlos G., Palsgrove, Doreen N., Sivakumar, Ananyaa, Elledge, Christen R., Kleinberg, Lawrence R., Chaichana, Kaisorn L., Gocke, Christopher D., Rodriguez, Fausto J., Holdhoff, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368694/
https://www.ncbi.nlm.nih.gov/pubmed/30738431
http://dx.doi.org/10.1186/s13000-019-0793-5

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