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Predicting clinically promising therapeutic hypotheses using tensor factorization

BACKGROUND: Determining which target to pursue is a challenging and error-prone first step in developing a therapeutic treatment for a disease, where missteps are potentially very costly given the long-time frames and high expenses of drug development. With current informatics technology and machine...

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Detalles Bibliográficos
Autores principales: Yao, Jin, Hurle, Mark R., Nelson, Matthew R., Agarwal, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368709/
https://www.ncbi.nlm.nih.gov/pubmed/30736745
http://dx.doi.org/10.1186/s12859-019-2664-1