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Stroke aetiological classification reliability and effect on trial sample size: systematic review, meta-analysis and statistical modelling

BACKGROUND: Inter-observer variability in stroke aetiological classification may have an effect on trial power and estimation of treatment effect. We modelled the effect of misclassification on required sample size in a hypothetical cardioembolic (CE) stroke trial. METHODS: We performed a systematic...

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Detalles Bibliográficos
Autores principales:	Abdul-Rahim, Azmil H., Dickie, David Alexander, Selvarajah, Johann R., Lees, Kennedy R., Quinn, Terence J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368715/ https://www.ncbi.nlm.nih.gov/pubmed/30736833 http://dx.doi.org/10.1186/s13063-019-3222-x

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