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Are tumor size changes predictive of survival for checkpoint blockade based immunotherapy in metastatic melanoma?
BACKGROUND: In oncology clinical development, objective response rate, disease control rate and early tumor size changes are commonly used as efficacy metrics for early decision-making. However, for immunotherapy trials, it is unclear whether these early efficacy metrics are still predictive of long...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368769/ https://www.ncbi.nlm.nih.gov/pubmed/30736858 http://dx.doi.org/10.1186/s40425-019-0513-4 |