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Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome

Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped. The patient had drug resistant epilepsy and failed anti-sei...

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Autores principales: Lee, Sydney, Denton, Alyssa, Ladino, Lady Diana, Waterhouse, Karen, Vitali, Aleksander, Tellez-Zenteno, Jose Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369242/
https://www.ncbi.nlm.nih.gov/pubmed/30788214
http://dx.doi.org/10.1016/j.ebcr.2019.01.004
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author Lee, Sydney
Denton, Alyssa
Ladino, Lady Diana
Waterhouse, Karen
Vitali, Aleksander
Tellez-Zenteno, Jose Francisco
author_facet Lee, Sydney
Denton, Alyssa
Ladino, Lady Diana
Waterhouse, Karen
Vitali, Aleksander
Tellez-Zenteno, Jose Francisco
author_sort Lee, Sydney
collection PubMed
description Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped. The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy. The patient had multiple types of seizures including drop attacks, absences, and tonic–clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off. This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator.
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spelling pubmed-63692422019-02-20 Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome Lee, Sydney Denton, Alyssa Ladino, Lady Diana Waterhouse, Karen Vitali, Aleksander Tellez-Zenteno, Jose Francisco Epilepsy Behav Case Rep Article Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped. The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy. The patient had multiple types of seizures including drop attacks, absences, and tonic–clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off. This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator. Elsevier 2019-01-27 /pmc/articles/PMC6369242/ /pubmed/30788214 http://dx.doi.org/10.1016/j.ebcr.2019.01.004 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Lee, Sydney
Denton, Alyssa
Ladino, Lady Diana
Waterhouse, Karen
Vitali, Aleksander
Tellez-Zenteno, Jose Francisco
Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome
title Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome
title_full Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome
title_fullStr Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome
title_full_unstemmed Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome
title_short Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome
title_sort forced normalization after turning off vagus nerve stimulation in lennox–gastaut syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369242/
https://www.ncbi.nlm.nih.gov/pubmed/30788214
http://dx.doi.org/10.1016/j.ebcr.2019.01.004
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