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Amelanocytic anorectal malignant melanoma—Case report
INTRODUCTION: Anorectal malignant melanoma (AMM), is a rare and aggressive form of melanoma. Accounts for <2% of melanomas, and <2% of anal tumors. It is more frequent at the 6(th)–7(th) decade, mostly in women. Surgery is the mainstay of treatment, but the extent is controversial. CASE PRESEN...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369256/ https://www.ncbi.nlm.nih.gov/pubmed/30739873 http://dx.doi.org/10.1016/j.ijscr.2019.01.029 |
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author | Serra, Marta Santos, Teresa Martins, Margarida Sardo, Leonor |
author_facet | Serra, Marta Santos, Teresa Martins, Margarida Sardo, Leonor |
author_sort | Serra, Marta |
collection | PubMed |
description | INTRODUCTION: Anorectal malignant melanoma (AMM), is a rare and aggressive form of melanoma. Accounts for <2% of melanomas, and <2% of anal tumors. It is more frequent at the 6(th)–7(th) decade, mostly in women. Surgery is the mainstay of treatment, but the extent is controversial. CASE PRESENTATION: 82-year-old male, presented with rectal mass in the Emergency Room (ER). After local excision, pathology observed that the mass corresponded to AMM. Despite being stage I (Local disease), a year later it presented with local recurrence and distant metastasis. The patient died 32 months after diagnosis. CONCLUSIONS: There is no optimal treatment, due to the lack of prospective studies. Wide local excision (WLE) has faster recovery, less post-operatory complications and similar survival rate compared to abdominal perineal resection (APR). |
format | Online Article Text |
id | pubmed-6369256 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-63692562019-02-20 Amelanocytic anorectal malignant melanoma—Case report Serra, Marta Santos, Teresa Martins, Margarida Sardo, Leonor Int J Surg Case Rep Article INTRODUCTION: Anorectal malignant melanoma (AMM), is a rare and aggressive form of melanoma. Accounts for <2% of melanomas, and <2% of anal tumors. It is more frequent at the 6(th)–7(th) decade, mostly in women. Surgery is the mainstay of treatment, but the extent is controversial. CASE PRESENTATION: 82-year-old male, presented with rectal mass in the Emergency Room (ER). After local excision, pathology observed that the mass corresponded to AMM. Despite being stage I (Local disease), a year later it presented with local recurrence and distant metastasis. The patient died 32 months after diagnosis. CONCLUSIONS: There is no optimal treatment, due to the lack of prospective studies. Wide local excision (WLE) has faster recovery, less post-operatory complications and similar survival rate compared to abdominal perineal resection (APR). Elsevier 2019-01-31 /pmc/articles/PMC6369256/ /pubmed/30739873 http://dx.doi.org/10.1016/j.ijscr.2019.01.029 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Serra, Marta Santos, Teresa Martins, Margarida Sardo, Leonor Amelanocytic anorectal malignant melanoma—Case report |
title | Amelanocytic anorectal malignant melanoma—Case report |
title_full | Amelanocytic anorectal malignant melanoma—Case report |
title_fullStr | Amelanocytic anorectal malignant melanoma—Case report |
title_full_unstemmed | Amelanocytic anorectal malignant melanoma—Case report |
title_short | Amelanocytic anorectal malignant melanoma—Case report |
title_sort | amelanocytic anorectal malignant melanoma—case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369256/ https://www.ncbi.nlm.nih.gov/pubmed/30739873 http://dx.doi.org/10.1016/j.ijscr.2019.01.029 |
work_keys_str_mv | AT serramarta amelanocyticanorectalmalignantmelanomacasereport AT santosteresa amelanocyticanorectalmalignantmelanomacasereport AT martinsmargarida amelanocyticanorectalmalignantmelanomacasereport AT sardoleonor amelanocyticanorectalmalignantmelanomacasereport |