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Amelanocytic anorectal malignant melanoma—Case report

INTRODUCTION: Anorectal malignant melanoma (AMM), is a rare and aggressive form of melanoma. Accounts for <2% of melanomas, and <2% of anal tumors. It is more frequent at the 6(th)–7(th) decade, mostly in women. Surgery is the mainstay of treatment, but the extent is controversial. CASE PRESEN...

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Autores principales: Serra, Marta, Santos, Teresa, Martins, Margarida, Sardo, Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369256/
https://www.ncbi.nlm.nih.gov/pubmed/30739873
http://dx.doi.org/10.1016/j.ijscr.2019.01.029
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author Serra, Marta
Santos, Teresa
Martins, Margarida
Sardo, Leonor
author_facet Serra, Marta
Santos, Teresa
Martins, Margarida
Sardo, Leonor
author_sort Serra, Marta
collection PubMed
description INTRODUCTION: Anorectal malignant melanoma (AMM), is a rare and aggressive form of melanoma. Accounts for <2% of melanomas, and <2% of anal tumors. It is more frequent at the 6(th)–7(th) decade, mostly in women. Surgery is the mainstay of treatment, but the extent is controversial. CASE PRESENTATION: 82-year-old male, presented with rectal mass in the Emergency Room (ER). After local excision, pathology observed that the mass corresponded to AMM. Despite being stage I (Local disease), a year later it presented with local recurrence and distant metastasis. The patient died 32 months after diagnosis. CONCLUSIONS: There is no optimal treatment, due to the lack of prospective studies. Wide local excision (WLE) has faster recovery, less post-operatory complications and similar survival rate compared to abdominal perineal resection (APR).
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spelling pubmed-63692562019-02-20 Amelanocytic anorectal malignant melanoma—Case report Serra, Marta Santos, Teresa Martins, Margarida Sardo, Leonor Int J Surg Case Rep Article INTRODUCTION: Anorectal malignant melanoma (AMM), is a rare and aggressive form of melanoma. Accounts for <2% of melanomas, and <2% of anal tumors. It is more frequent at the 6(th)–7(th) decade, mostly in women. Surgery is the mainstay of treatment, but the extent is controversial. CASE PRESENTATION: 82-year-old male, presented with rectal mass in the Emergency Room (ER). After local excision, pathology observed that the mass corresponded to AMM. Despite being stage I (Local disease), a year later it presented with local recurrence and distant metastasis. The patient died 32 months after diagnosis. CONCLUSIONS: There is no optimal treatment, due to the lack of prospective studies. Wide local excision (WLE) has faster recovery, less post-operatory complications and similar survival rate compared to abdominal perineal resection (APR). Elsevier 2019-01-31 /pmc/articles/PMC6369256/ /pubmed/30739873 http://dx.doi.org/10.1016/j.ijscr.2019.01.029 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Serra, Marta
Santos, Teresa
Martins, Margarida
Sardo, Leonor
Amelanocytic anorectal malignant melanoma—Case report
title Amelanocytic anorectal malignant melanoma—Case report
title_full Amelanocytic anorectal malignant melanoma—Case report
title_fullStr Amelanocytic anorectal malignant melanoma—Case report
title_full_unstemmed Amelanocytic anorectal malignant melanoma—Case report
title_short Amelanocytic anorectal malignant melanoma—Case report
title_sort amelanocytic anorectal malignant melanoma—case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369256/
https://www.ncbi.nlm.nih.gov/pubmed/30739873
http://dx.doi.org/10.1016/j.ijscr.2019.01.029
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