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Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis

To select more effective feature genes, many existing algorithms focus on the selection and study of evaluation methods for feature genes, ignoring the accurate mapping of original information in data processing. Therefore, for solving this problem, a new model is proposed in this paper: rough uncer...

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Detalles Bibliográficos
Autores principales: Xu, Jiucheng, Wang, Yun, Xu, Keqiang, Zhang, Tianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369463/
https://www.ncbi.nlm.nih.gov/pubmed/30809269
http://dx.doi.org/10.1155/2019/6705648
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author Xu, Jiucheng
Wang, Yun
Xu, Keqiang
Zhang, Tianli
author_facet Xu, Jiucheng
Wang, Yun
Xu, Keqiang
Zhang, Tianli
author_sort Xu, Jiucheng
collection PubMed
description To select more effective feature genes, many existing algorithms focus on the selection and study of evaluation methods for feature genes, ignoring the accurate mapping of original information in data processing. Therefore, for solving this problem, a new model is proposed in this paper: rough uncertainty metric model. First, the fuzzy neighborhood granule of the sample is constructed by combining the fuzzy similarity relation with the neighborhood radius in the rough set, and the rough decision is defined by using the fuzzy similarity relation and the decision equivalence class. Then, the fuzzy neighborhood granule and the rough decision are introduced into the conditional entropy, and the rough uncertainty metric model is proposed; in the meantime, the definition of measuring the significance of feature genes and the proof of some related theorems are given. To make this model tolerate noises in data, this paper introduces a variable precision model and discusses the selection of parameters. Finally, based on the rough uncertainty metric model, we design a feature genes selection algorithm and compare it with some existing similar algorithms. The experimental results show that the proposed algorithm can select the smaller feature genes subset with higher classification accuracy and verify that the model proposed in this paper is more effective.
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spelling pubmed-63694632019-02-26 Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis Xu, Jiucheng Wang, Yun Xu, Keqiang Zhang, Tianli Comput Math Methods Med Research Article To select more effective feature genes, many existing algorithms focus on the selection and study of evaluation methods for feature genes, ignoring the accurate mapping of original information in data processing. Therefore, for solving this problem, a new model is proposed in this paper: rough uncertainty metric model. First, the fuzzy neighborhood granule of the sample is constructed by combining the fuzzy similarity relation with the neighborhood radius in the rough set, and the rough decision is defined by using the fuzzy similarity relation and the decision equivalence class. Then, the fuzzy neighborhood granule and the rough decision are introduced into the conditional entropy, and the rough uncertainty metric model is proposed; in the meantime, the definition of measuring the significance of feature genes and the proof of some related theorems are given. To make this model tolerate noises in data, this paper introduces a variable precision model and discusses the selection of parameters. Finally, based on the rough uncertainty metric model, we design a feature genes selection algorithm and compare it with some existing similar algorithms. The experimental results show that the proposed algorithm can select the smaller feature genes subset with higher classification accuracy and verify that the model proposed in this paper is more effective. Hindawi 2019-01-27 /pmc/articles/PMC6369463/ /pubmed/30809269 http://dx.doi.org/10.1155/2019/6705648 Text en Copyright © 2019 Jiucheng Xu et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Xu, Jiucheng
Wang, Yun
Xu, Keqiang
Zhang, Tianli
Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis
title Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis
title_full Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis
title_fullStr Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis
title_full_unstemmed Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis
title_short Feature Genes Selection Using Fuzzy Rough Uncertainty Metric for Tumor Diagnosis
title_sort feature genes selection using fuzzy rough uncertainty metric for tumor diagnosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369463/
https://www.ncbi.nlm.nih.gov/pubmed/30809269
http://dx.doi.org/10.1155/2019/6705648
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