Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression

The impact of mitochondrial dysfunction in epigenetics is emerging, but our understanding of this relationship and its effect on gene expression remains incomplete. We previously showed that acute mitochondrial DNA (mtDNA) loss leads to histone hypoacetylation. It remains to be defined if these chan...

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Detalles Bibliográficos
Autores principales: Lozoya, Oswaldo A, Wang, Tianyuan, Grenet, Dagoberto, Wolfgang, Taylor C, Sobhany, Mack, Ganini da Silva, Douglas, Riadi, Gonzalo, Chandel, Navdeep, Woychik, Richard P, Santos, Janine H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369536/
https://www.ncbi.nlm.nih.gov/pubmed/30737248
http://dx.doi.org/10.26508/lsa.201800228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369536/
https://www.ncbi.nlm.nih.gov/pubmed/30737248
http://dx.doi.org/10.26508/lsa.201800228

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