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Endothelial edema precedes blood-brain barrier breakdown in early time points after experimental focal cerebral ischemia

In the setting of stroke, ischemia-related blood-brain barrier (BBB) dysfunction aggravates the cerebral edema, which critically impacts on the clinical outcome. Further, an impaired vascular integrity is associated with the risk of intracranial bleeding, especially after therapeutic recanalization....

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Detalles Bibliográficos
Autores principales: Krueger, Martin, Mages, Bianca, Hobusch, Constance, Michalski, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369548/
https://www.ncbi.nlm.nih.gov/pubmed/30744693
http://dx.doi.org/10.1186/s40478-019-0671-0