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Endothelial edema precedes blood-brain barrier breakdown in early time points after experimental focal cerebral ischemia
In the setting of stroke, ischemia-related blood-brain barrier (BBB) dysfunction aggravates the cerebral edema, which critically impacts on the clinical outcome. Further, an impaired vascular integrity is associated with the risk of intracranial bleeding, especially after therapeutic recanalization....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369548/ https://www.ncbi.nlm.nih.gov/pubmed/30744693 http://dx.doi.org/10.1186/s40478-019-0671-0 |