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Understanding the Cross-Talk of Redox Metabolism and Fe-S Cluster Biogenesis in Leishmania Through Systems Biology Approach
Leishmania parasites possess an exceptional oxidant and chemical defense mechanism, involving a very unique small molecular weight thiol, trypanothione (T[SH](2)), that helps the parasite to manage its survival inside the host macrophage. The reduced state of T[SH](2) is maintained by NADPH-dependen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369582/ https://www.ncbi.nlm.nih.gov/pubmed/30778378 http://dx.doi.org/10.3389/fcimb.2019.00015 |