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Exogenous Addition of 25‐Hydroxycholesterol Reduces Level of Very Long‐Chain Fatty Acids in X‐Linked Adrenoleukodystrophy
X‐Linked adrenoleukodystrophy (X‐ALD) is a severe metabolic disorder characterized by the accumulation of very long‐chain fatty acids (VLCFAs). Recently, we demonstrated that levels of 25‐hydroxycholesterol (25‐HC) and cholesterol 25‐hydroxylase (CH25H) were found to be elevated in X‐ALD. Herein, we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369660/ https://www.ncbi.nlm.nih.gov/pubmed/30788208 http://dx.doi.org/10.1002/open.201800281 |