Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer

Circulating tumor cells (CTCs) play a fundamental role in cancer progression. However, in mice, limited blood volume and the rarity of CTCs in the bloodstream preclude longitudinal, in-depth studies of these cells using existing liquid biopsy techniques. Here, we present an optofluidic system that c...

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Detalles Bibliográficos
Autores principales: Hamza, Bashar, Ng, Sheng Rong, Prakadan, Sanjay M., Delgado, Francisco Feijó, Chin, Christopher R., King, Emily M., Yang, Lucy F., Davidson, Shawn M., DeGouveia, Kelsey L., Cermak, Nathan, Navia, Andrew W., Winter, Peter S., Drake, Riley S., Tammela, Tuomas, Li, Carman Man-Chung, Papagiannakopoulos, Thales, Gupta, Alejandro J., Shaw Bagnall, Josephine, Knudsen, Scott M., Vander Heiden, Matthew G., Wasserman, Steven C., Jacks, Tyler, Shalek, Alex K., Manalis, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369805/
https://www.ncbi.nlm.nih.gov/pubmed/30674677
http://dx.doi.org/10.1073/pnas.1814102116

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