Balancing selection at a premature stop mutation in the myostatin gene underlies a recessive leg weakness syndrome in pigs

Balancing selection provides a plausible explanation for the maintenance of deleterious alleles at moderate frequency in livestock, including lethal recessives exhibiting heterozygous advantage in carriers. In the current study, a leg weakness syndrome causing mortality of piglets in a commercial li...

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Detalles Bibliográficos
Autores principales: Matika, Oswald, Robledo, Diego, Pong-Wong, Ricardo, Bishop, Stephen C., Riggio, Valentina, Finlayson, Heather, Lowe, Natalie R., Hoste, Annabelle E., Walling, Grant A., del-Pozo, Jorge, Archibald, Alan L., Woolliams, John A., Houston, Ross D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370237/
https://www.ncbi.nlm.nih.gov/pubmed/30699111
http://dx.doi.org/10.1371/journal.pgen.1007759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370237/
https://www.ncbi.nlm.nih.gov/pubmed/30699111
http://dx.doi.org/10.1371/journal.pgen.1007759

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