Cargando…
Mechanistic framework predicts drug-class specific utility of antiretrovirals for HIV prophylaxis
Currently, there is no effective vaccine to halt HIV transmission. However, pre-exposure prophylaxis (PrEP) with the drug combination Truvada can substantially decrease HIV transmission in individuals at risk. Despite its benefits, Truvada-based PrEP is expensive and needs to be taken once-daily, wh...
Autores principales: | Duwal, Sulav, Dickinson, Laura, Khoo, Saye, von Kleist, Max |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370240/ https://www.ncbi.nlm.nih.gov/pubmed/30699105 http://dx.doi.org/10.1371/journal.pcbi.1006740 |
Ejemplares similares
-
Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes
por: Duwal, Sulav, et al.
Publicado: (2018) -
The Utility of Efavirenz-based Prophylaxis Against HIV Infection. A Systems Pharmacological Analysis
por: Duwal, Sulav, et al.
Publicado: (2019) -
Pharmacokinetics and Pharmacodynamics of the Reverse Transcriptase Inhibitor Tenofovir and Prophylactic Efficacy against HIV-1 Infection
por: Duwal, Sulav, et al.
Publicado: (2012) -
Correction: Pharmacokinetics and Pharmacodynamics of the Reverse Transcriptase Inhibitor Tenofovir and Prophylactic Efficacy against HIV-1 Infection
por: Duwal, Sulav, et al.
Publicado: (2012) -
Optimal Treatment Strategies in the Context of ‘Treatment for Prevention’ against HIV-1 in Resource-Poor Settings
por: Duwal, Sulav, et al.
Publicado: (2015)