Cargando…
Ag(I)–C–H Activation Enables Near-Room-Temperature Direct α-Arylation of Benzo[b]thiophenes
[Image: see text] The first example of near-room-temperature α-arylation of benzo[b]thiophenes is reported. The discovery rests on the observation of a switch in α-/β-regioselectivity at different loadings of Pd(2)(dba)(3)·CHCl(3) in the coupling between benzo[b]thiophene and 4-iodotoluene. We show...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370252/ https://www.ncbi.nlm.nih.gov/pubmed/29983049 http://dx.doi.org/10.1021/jacs.8b05361 |