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Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related deaths, warranting better therapies. Restoration of tumor-suppressive microRNAs depleted in hepatocellular carcinoma represents a new therapeutic strategy. Herein, we sought to identify a potent microRNA (miRNA) agent that coul...

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Detalles Bibliográficos
Autores principales:	Jilek, Joseph L., Zhang, Qian-Yu, Tu, Mei-Juan, Ho, Pui Yan, Duan, Zhijian, Qiu, Jing-Xin, Yu, Ai-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370598/ https://www.ncbi.nlm.nih.gov/pubmed/30753993 http://dx.doi.org/10.1016/j.omtn.2019.01.007

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